| N A M E | O R I G I N | M E A N I N G |
| Sim | Gaelic | Heard. |
| Siman | Czechoslovakian | Heard. |
| Simao | Hebrew | Obedient. |
| Simen | Hebrew | Obedient. |
| Simeon | Latin | He Heard |
| Simon | Hebrew | he who hears |
| Simpson | Hebrew | Son of Simon. |
| Simson | Hebrew | Son of Simon. |
| Sinai | Hebrew | From the clay desert. |
| Sinclair | French | Saint Clair |
| Sinclaire | English | St. Clair. |
| Sindri | Norse | A mythical dwarf. |
| Sinfiotli | Norse | Son of Siggeir. |
| Singh | Hindu | lion |
| Sinjin | English | Saint John |
| Sinjon | French | Saint John |
| Sinley | Anglo-Saxon | Friendly. |
| Sinnoch | Welsh | Legendary son of Seithved. |
| Sinon | Greek | Convinced the Trojans to pull the horse inside the city walls. |
| Siodhachan | Irish | Little peaceful one. |
| Siolat | Gaelic | Teal duck. |
| Siomon | Hebrew | Obedient. |
| Sion | Welsh | Welsh form of John 'God is gracious'. |
| Sior | Welsh | Welsh form of George 'farmer'. |
| Sippai | Biblical | Threshold, silver cup. |
| Sirius | Greek | Sparkling, Scorching |
| Sisamai | Biblical | House, blindness. |
| Siseal | Latin | Blind. |
| Sisera | Biblical | That sees a horse or a swallow. |
| Sisyphus | Greek | Son of Aelous. |
